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・ 39th United States Congress
・ 39th Vanier Cup
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・ 39th Virginia Infantry
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・ 39th World Science Fiction Convention
・ 3@Three
・ 3A
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・ 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
3alpha(or 20beta)-hydroxysteroid dehydrogenase
・ 3alpha(S)-strictosidine beta-glucosidase
・ 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
・ 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase
・ 3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase
・ 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase
・ 3alpha-hydroxycholanate dehydrogenase
・ 3alpha-hydroxyglycyrrhetinate dehydrogenase
・ 3alpha-hydroxysteroid dehydrogenase (A-specific)
・ 3alpha-hydroxysteroid dehydrogenase (B-specific)
・ 3AM (Kleerup song)
・ 3AM (Matchbox Twenty song)
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3alpha(or 20beta)-hydroxysteroid dehydrogenase : ウィキペディア英語版
3alpha(or 20beta)-hydroxysteroid dehydrogenase

In enzymology, a 3alpha(or 20beta)-hydroxysteroid dehydrogenase () is an enzyme that catalyzes the chemical reaction
:androstan-3alpha,17beta-diol + NAD+ \rightleftharpoons 17beta-hydroxyandrostan-3-one + NADH + H+
Thus, the two substrates of this enzyme are androstan-3alpha,17beta-diol and NAD+, whereas its 3 products are 17beta-hydroxyandrostan-3-one, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase. Other names in common use include cortisone reductase, (R)-20-hydroxysteroid dehydrogenase, dehydrogenase, 20beta-hydroxy steroid, Delta4-3-ketosteroid hydrogenase, 20beta-hydroxysteroid dehydrogenase, 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase, NADH-20beta-hydroxysteroid dehydrogenase, and 20beta-HSD. This enzyme participates in bile acid biosynthesis and c21-steroid hormone metabolism.
==Structural studies==

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes , , , , , and .

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